Reacción #1161787

ord-4a2fd17b923e41f39038038a09e12b67

Ecuación de reacción

CC(C)c1ccccc1NC(=O)CC#N
2-cyano-2'-isopropylacetanilide
COC(C)(OC)N(C)C
N,N-dimethylacetamide dimethylacetal
→
C/C(=C(\C#N)C(=O)Nc1ccccc1C(C)C)N(C)C
2-cyano-3-dimethylamino-2'-isopropylcrotonanilide

Reactantes

CC(C)c1ccccc1NC(=O)CC#N
2-cyano-2'-isopropylacetanilide
COC(C)(OC)N(C)C
N,N-dimethylacetamide dimethylacetal

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

As for Example 1, 2-cyano-2'-isopropylacetanilide, off-white crystals, m.p. 74°-78° C. (prepared by the procedure described in U.S. Pat. No. 3,116,312), is heated with N,N-dimethylacetamide dimethylacetal to yield 2-cyano-3-dimethylamino-2'-isopropylcrotonanilide as colorless prisms, m.p. 119°-121° C.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US04393217uspto-grants-1983_07