Reacción #1152352

Ecuación de reacción

7-chloro-4-trimethylsilyloxy-4-vinyl-1-heptyne

tri-n-butylstannane

→

oil

Rendimiento 80.0%

E-7-Chloro-4-trimethylsilyloxy-4-vinyl-1-tri-n-butylstannyl-1-heptene

Rendimiento 80.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   TemperaturaAfter cooling
2. 2
   Otrothe unreacted tri-n-butylstannane is removed by distillation via Kuglerohr (140°, 0.5-0.3 mm)

Procedimiento

A mixture of 7-chloro-4-trimethylsilyloxy-4-vinyl-1-heptyne (17 g, 0.07 mol) and 20.7 g (0.71 mol) of tri-n-butylstannane and 150 mg of azobisisobutrylnitrile (AIBN) is stirred under argon in a 140° oil bath behind a safety shield. After 3 minutes an exotherm occurs and the mixture is maintained at 140° C. for 1.5 hr. After cooling, air is admitted and the unreacted tri-n-butylstannane is removed by distillation via Kuglerohr (140°, 0.5-0.3 mm) to give a very light yellow oil (30 g). This oil consists of a mixture of the E and Z isomers.

Fuente