Reacción #11398

Ecuación de reacción

5-amino-1-cyclopropyl-6,7-difluoro-8-methoxy-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid

4-methylamino-3,3-dimethylpiperidine

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titled product

Rendimiento 54.0%

5-Amino-1-cyclopropyl-6-fluoro-8-methoxy-1,4-dihydro-7-{4′-(methylamino)-3′,3′-dimethylpiperidin-1-yl}-4-oxo-quinoline-3-carboxylic acid

Rendimiento 54.0%

Condiciones de reacción

Procedimiento

The condensation of 5-amino-1-cyclopropyl-6,7-difluoro-8-methoxy-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid with 4-methylamino-3,3-dimethylpiperidine was carried out in a similar manner as described in example 1 (NorA), gave the titled product. Yield 54%, m.p 250° C., C22H29FN4O4, m/z 433 (M+1).

Fuente