Reacción #11366

Ecuación de reacción

compound

2-(2-Ethoxyphenyl)-5-methyl-7-cycloheptyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-one

bromoacetyl bromide

aluminum trichloride

→

desired product

Rendimiento 66.5%

2-[5-(2-Bromoacetyl)-2-ethoxyphenyl]-5-methyl-7-cycloheptyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-one

Rendimiento 66.5%

Disolventes

ether

Condiciones de reacción

Procedimiento

Analogously to example 57A, 1.36 g (3.7 mmol) of the compound from example 28A were reacted with 1.5 g (7.4 mmol) of bromoacetyl bromide and 1.48 g (1.1 mmol) of aluminum trichloride. Trituration with ether gave 1.2 g (66.3%) of the desired product.

Fuente