Reacción #1135798

Ecuación de reacción

1-chloro-2-methyl-3-methoxycarbonylaminobenzene

phosphorus pentachloride

→

1-chloro-3-isocyanato-2-methylbenzene

Disolventes

chlorobenzene

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturawith heating
2. 2
   Temperaturaunder reflux for one hour
3. 3
   OtroThe reaction mixtures
4. 4
   Concentraciónwere concentrated under reduced pressure

Procedimiento

A mixture of the above-mentioned 1-chloro-2-methyl-3-methoxycarbonylaminobenzene 5.80 g, phosphorus pentachloride 7.53 g and chlorobenzene 50 mL was stirred with heating under reflux for one hour. The reaction mixtures were concentrated under reduced pressure to give 1-chloro-3-isocyanato-2-methylbenzene.

Fuente