Reacción #11356

Ecuación de reacción

2-hydroxybenzonitrile

potassium carbonate

ethyl bromide

→

2-Ethoxybenzonitrile

Disolventes

acetone

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe solid is filtered off
2. 2
   Otrothe solvent is removed under reduced pressure
3. 3
   workup.DISTILLATIONthe residue is distilled under reduced pressure

Procedimiento

25 g (210 mmol) of 2-hydroxybenzonitrile, 87 g of potassium carbonate and 34.3 g (314.8 mmol) of ethyl bromide are refluxed in 500 ml of acetone overnight. The solid is filtered off, the solvent is removed under reduced pressure and the residue is distilled under reduced pressure. This gives 30.0 g (97%) of a colorless liquid.

Fuente