Reacción #11287

Ecuación de reacción

4,8-dimethyl-3,7-nonadien-2-ol

pyridine

water

→

crude product

Rendimiento 76.0%

4,8-Dimethyl-3,7-nonadien-2-yl Butyrate

Rendimiento 76.0%

Disolventes

methyl t-butyl ether

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturacooled to room temperature
2. 2
   Lavadowashed several times with water until neutral pH
3. 3
   Secadodried over sodium sulfate
4. 4
   Concentraciónconcentrated

Procedimiento

A flask was charged with 4,8-dimethyl-3,7-nonadien-2-ol CAS 67845-50-5 (20 grams), buryric anhydride (25 grams) and pyridine (12.5 grams). The mixture was stirred and heated to 100° C. The reaction was held at 100° C.±1° C. for 90 minutes and then cooled to room temperature. The reaction mixture was diluted with water (100 milliliters) and methyl t-butyl ether, washed several times with water until neutral pH, dried over sodium sulfate and concentrated to furnish 34.4 grams of crude product. After distillation by Kugelruhr 23.4 g of the product, 76% yield, were obtained and confirmed by 1H NMR.

Fuente