Reacción #11218

ord-c4c6b20ef05246859197c01fa797a32d

Ecuación de reacción

COc1cc2cc(C=Cc3ccccc3Cl)[nH]c2cc1OCc1ccccc1
diene
COc1cc2cc(C=Cc3ccccc3Cl)[nH]c2cc1OCc1ccccc1
6-(Benzyloxy)-2-[2-(2-chlorophenyl)ethenyl]-5-methoxy-1H-indole
O=C1C=CC(=O)N1
maleimide
COc1cc2c3c([nH]c2cc1OCc1ccccc1)CC(c1ccccc1Cl)C1C(=O)NC(=O)C31
adduct ( 161 )
Rendimiento 87.0%
COc1cc2c3c([nH]c2cc1OCc1ccccc1)CC(c1ccccc1Cl)C1C(=O)NC(=O)C31
8-(Benzyloxy)-4-(2-chlorophenyl)-9-methoxy-4,5,6,10c-tetrahydropyrrolo[3,4-c]carbazole-1,3(2H,3aH)-dione
Rendimiento 87.0%

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    Otroprepared

Procedimiento

Reaction of the diene (155) prepared as described in example 255 with maleimide using the procedure described in example 69 gave the adduct (161) as a tan powder (87%), which was used without further purification.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07094798B1uspto-grants-2006_08