Reacción #11078

Ecuación de reacción

intermediate 22b

3-benzyloxycarbonylamino-6-ethyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic acid

[(4-aminomethyl-phenyl)-imino-methyl]-carbamic acid tert-butyl ester

→

intermediate 22c

Rendimiento 100.0%

{6-[4-(tert-butoxycarbonylamino-imino-methyl)-benzylcarbamoyl]-6-ethyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidin-3-yl}-carbamic acid benzyl ester

Rendimiento 100.0%

Condiciones de reacción

Procedimiento

According to the procedure for the preparation of intermediate 19c, intermediate 22b (34.5 mg, 0.0965 mmol) was coupled with [(4-aminomethyl-phenyl)-imino-methyl]-carbamic acid tert-butyl ester to afford 57 mg (100%) of intermediate 22c.

Fuente