Reacción #1106682

Ecuación de reacción

C-Benzo[1,3]dioxol-2-yl-methylamine

sulfamide

→

title compound

(Benzo[1,3]dioxol-2-ylmethyl)sulfamide

Disolventes

dioxane

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturathe solution was heated
2. 2
   Temperaturato reflux overnight
3. 3
   ConcentraciónThe reaction was concentrated
4. 4
   Otrothe residue was chromatographed (2% to 10% acetone in dichloromethane)

Procedimiento

C-Benzo[1,3]dioxol-2-yl-methylamine (2.94 g, 19.4 mmol) and sulfamide (3.74 g, 38.9 mmol) were combined in dry dioxane (50 mL) and the solution was heated to reflux overnight. The reaction was concentrated and the residue was chromatographed (2% to 10% acetone in dichloromethane) to yield the title compound as a white solid.

Fuente