Reacción #11046
ord-d92c58b0faca44eeb43c64c494c5501b
Ecuación de reacción
Ethyl 3-phenyl-3-{[3′-(1,3-thiazol-2-ylamino)[1,1′-biphenyl]-3-yl]sulfonylamino}-propanoate
dichloromethane methanol
dichloromethane acetic acid ethyl ester
→
3-phenyl-3-{[3′-(1,3-thiazol-2-ylamino)[1,1′-biphenyl]-3-yl]sulfonylamino}-propanoic acid
Reactantes
Reactivos
Ninguno
Disolventes
Condiciones de reacción
Condiciones detalladas
See reaction.notes.procedure_details.
Procedimiento
0.2 g of Ethyl 3-phenyl-3-{[3′-(1,3-thiazol-2-ylamino)[1,1′-biphenyl]-3-yl]sulfonylamino}-propanoate 15.1.1 were saponified in 15 ml dimethoxyethane 12 ml water and 0.2 g LiOH. After aqueos work-up and flash chromatography (dichloromethane/methanol 10+1) 65 mg were obtained.