Reacción #1100095

ord-2a0566a11c9f416684e2ea85dc7d01f7

Ecuación de reacción

NC1CCC(C(=O)c2nc3ccccc3s2)CC1
(4-amino-cyclohexyl)-benzothiazol-2-yl-methanone
O=Cc1ccc2c(c1)NC(=O)CO2
3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbaldehyde
O=C1COc2ccc(CN[C@H]3CC[C@H](C(=O)c4nc5ccccc5s4)CC3)cc2N1
title compound
Rendimiento 31.6%
O=C1COc2ccc(CN[C@H]3CC[C@H](C(=O)c4nc5ccccc5s4)CC3)cc2N1
6-{[trans-4-(benzothiazole-2-carbonyl)-cyclohexylamino]-methyl}-4H-benzo[1,4]oxazin-3-one
Rendimiento 31.6%

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    OtroThe title compound was prepared

Procedimiento

The title compound was prepared according to the same protocol as for example 1, step 1.c, using however (4-amino-cyclohexyl)-benzothiazol-2-yl-methanone (0.3 mmol) and 3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbaldehyde (0.3 mmol). 40 mg (28%) of the title compound (a yellowish solid) were obtained.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07981886B2uspto-grants-2011_07