Reacción #1097

ord-7b37c31faaef4c5bb1868f6f9352f189

Ecuación de reacción

COc1c(Cl)ccnc1C
4-chloro-3-methoxy-2-methylpyridine
CC(C)(C)c1ccc(CON)cc1
O-(4-tert-butylbenzyl)hydroxylamine
→
COc1c(NOCc2ccc(C(C)(C)C)cc2)ccnc1C
4-[O-(4-tert-Butylbenzyl)hydroxylamino]-3-methoxy-2-methylpyridine
Rendimiento 80.0%

Reactantes

COc1c(Cl)ccnc1C
4-chloro-3-methoxy-2-methylpyridine
CC(C)(C)c1ccc(CON)cc1
O-(4-tert-butylbenzyl)hydroxylamine

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Prepared analogously to Example 1 from 4-chloro-3-methoxy-2-methylpyridine and O-(4-tert-butylbenzyl)hydroxylamine. Yield: 80%; m.p.: 113° C.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US05723450uspto-grants-1998_03