Reacción #10945

ord-128369000365468e8ac4191f5ff6d728

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Methyl 3-(5-fluoro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate was prepared (0.66 g, 47%) in the same manner as described in the above example 5 (1) from methyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionate (0.80 g, 5.07 mmol) and 4-fluorophthalic anhydride (0.80 g, 5.07 mmol), and the obtained product was identified with the following NMR data.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07094908B2uspto-grants-2006_08