Reacción #10692

ord-ff4b8c61b8b94d78ab0ae7c76692603a

Ecuación de reacción

Cl.O=S(=O)(Cl)c1cccc2cnccc12
isoquinoline-5-sulfonyl chloride hydrochloride
NCCCCN
1,4-butylenediamine
NCCCCNS(=O)(=O)c1cccc2cnccc12
title compound
Rendimiento 61.9%
NCCCCNS(=O)(=O)c1cccc2cnccc12
N-[(5-isoquinolyl)sulfonyl]-1,4-butylenediamine
Rendimiento 61.9%

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

According to the method of Reference Example 2, a reaction was performed by using isoquinoline-5-sulfonyl chloride hydrochloride (18.8 g) and 1,4-butylenediamine (25 g) to obtain the title compound (12.3 g).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07094789B2uspto-grants-2006_08