Reacción #1069016

Ecuación de reacción

sodium hydroxide

2'-Bromo-4'-nitro-1,2,2,3,3,4,4,5,5,6,6-undecafluorocyclohexanecarboxanilide

→

tetra-n-propylammonium

Rendimiento 75.9%

2'-Bromo-4'-nitro-1,2,2,3,3,4,4,5,5,6,6-undecafluorocyclohexanecarboxanilide, tetra-n-propylammonium salt

Rendimiento 75.9%

Disolventes

acetone

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroan oily solid separated
2. 2
   ExtracciónIt was extracted with diethyl ether
3. 3
   Secadodried over magnesium sulfate
4. 4
   Otroevaporated
5. 5
   Otrocrystallized at -10° C. from water/ethanol

Procedimiento

2'-Bromo-4'-nitro-1,2,2,3,3,4,4,5,5,6,6-undecafluorocyclohexanecarboxanilide (2.6 grams; 0.005 mole) was dissolved in 50 ml. of acetone and 1N sodium hydroxide (5.0 ml., 0.005 mole) was added all at once. Tetrapropylammonium bromide (1.35 gram; 0.005 mole) was then added and the reaction mixture was stirred until it became one phase. The reaction mixture was then poured over ice/water, and an oily solid separated. It was extracted with diethyl ether, dried over magnesium sulfate, evaporated, and crystallized at -10° C. from water/ethanol. 0.9 gram (25% yield) of the tetra-n-propylammonium salt was obtained, m.p., 86°-87° C.

Fuente