Reacción #1061091

Ecuación de reacción

2-ethylhexylamine

methyl carbamate

toluene

→

N-(2-ethylhexyl)urea

Rendimiento 91.7%

Disolventes

Methanol

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroInto a 300 ml reaction vessel
2. 2
   Otroequipped with a distillation apparatus
3. 3
   Temperaturaheated
4. 4
   Otrowas removed
5. 5
   Temperaturathe mixture was refluxed
6. 6
   Temperaturaby heating for 30 minutes
7. 7
   workup.STIRRINGwith stirring
8. 8
   Temperaturato cool
9. 9
   workup.DISTILLATIONThe toluene was distilled off under reduced pressure
10. 10
    Lavadothe residue was washed with n-hexane
11. 11
    Filtracióncollected by filtration

Procedimiento

Into a 300 ml reaction vessel equipped with a distillation apparatus were introduced 50 g of 2-ethylhexylamine, 29 g of methyl carbamate and 100 ml of toluene, and to the mixture was added 0.1 g of dibutyl tin oxide as a catalyst and heated with stirring. Methanol formed during the reaction was removed, when the reflux temperature was raised to 110° C., i.e., the boiling point of toluene, the distillation apparatus was taken off and instead a reflux condenser was attached and the mixture was refluxed by heating for 30 minutes with stirring, then allowed to cool. The toluene was distilled off under reduced pressure, and the residue was washed with n-hexane and collected by filtration to obtain 61 g of N-(2-ethylhexyl)urea.

Fuente