Reacción #10544

ord-a37b355baf0d4ccb87189a29d7e7e818

Ecuación de reacción

NC1CCCC1
cyclopentylamine
CC(C)=O
acetone
CC(C)NC1CCCC1
title compound
CC(C)NC1CCCC1
N-Isopropylcyclopentanamine

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    workup.STIRRINGAfter stirring for 16 hours the reaction mixture
  2. 2
    Filtraciónwas filtered through Arbocel (trade mark)
  3. 3
    Otrothe solvent removed under reduced pressure

Procedimiento

Peariman's catalyst (20% w/w palladium hydroxide-on-carbon) (1.5 g) was added to a solution of cyclopentylamine (15 ml, 0.21 mol) in acetone (200 ml). The reaction mixture was stirred under an atmosphere of hydrogen gas at 414 kPa (60 psi). After stirring for 16 hours the reaction mixture was filtered through Arbocel (trade mark) and the solvent removed under reduced pressure to give the title compound (15 ml) as a thin oil.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07094769B2uspto-grants-2006_08