Reacción #1016775

ord-5fe43679530b41eb98665fde661530ef

Ecuación de reacción

CC(C)(C)NCc1cc(-c2ccc(C(F)(F)F)c(Cl)c2)cc(-c2ccc(C(F)(F)F)c(Cl)c2)c1O
Intermediate 5
CC(C)(C)NCc1cc(-c2ccc(C(F)(F)F)c(Cl)c2)cc(-c2ccc(C(F)(F)F)c(Cl)c2)c1O
5′-((tert-Butylamino)methyl)-3,3″-dichloro-4,4″-bis(trifluoromethyl)-[1,1′:3′,1″-terphenyl]-4′-ol
O=Cc1cc(Br)cc(Br)c1O
3,5-dibromosalicylaldehyde
OB(O)c1ccc(C(F)(F)F)c(Cl)c1
3-chloro-4-(trifluoromethyl)phenylboronic acid
O=Cc1cc(-c2ccc(C(F)(F)F)c(Cl)c2)cc(-c2ccc(C(F)(F)F)c(Cl)c2)c1O
3,3″-Dichloro-4′-hydroxy-4,4″-bis(trifluoromethyl)-[1,1′:3′,1″-terphenyl]-5′-carbaldehyde

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

3,3″-Dichloro-4′-hydroxy-4,4″-bis(trifluoromethyl)-[1,1′:3′,1″-terphenyl]-5′-carbaldehyde was prepared using the procedure described in Intermediate 5 from 3,5-dibromosalicylaldehyde and 3-chloro-4-(trifluoromethyl)phenylboronic acid.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US09296696B2uspto-grants-2016_03