Reacción #1005986

Ecuación de reacción

phenol

4-bromo-2-cyclohex-2-enyl-phenol

MCPBA

→

8-bromo-1,2,3,4-tetrahydro-dibenzofuran-4-ol

Disolventes

benzene

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroA solid is precipitated out
2. 2
   Filtraciónfiltered
3. 3
   ConcentraciónThe filtrate is concentrated under vacuum
4. 4
   Otrochromatographed (10% EtOAc in hexanes)

Procedimiento

A solution of the phenol and MCPBA in benzene is refluxed overnight. A solid is precipitated out and filtered. The filtrate is concentrated under vacuum and chromatographed (10% EtOAc in hexanes) to give 8-bromo-1,2,3,4-tetrahydro-dibenzofuran-4-ol 108 as clear oil, 0.66 g, 39%.

Fuente