Reacción #1001828

ord-b714c76ad01f47cfa0c3dadb7662f22e

Ecuación de reacción

O=C(O)CCCCCCCCCCCCCCOc1c(I)cc(I)cc1I
15-(2,4,6-triiodophenoxy)pentadecanoic acid
CCOC(=O)CC(=O)OCC
diethyl malonate
→
O=C(O)CCCCCCCCCCCCCCCCOc1c(I)cc(I)cc1I
17-(2,4,6-triiodophenoxy)heptadecanoic acid

Reactantes

O=C(O)CCCCCCCCCCCCCCOc1c(I)cc(I)cc1I
15-(2,4,6-triiodophenoxy)pentadecanoic acid
CCOC(=O)CC(=O)OCC
diethyl malonate

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    workup.ADDITION(Weinheim) 328, 271 (1995), addition of two carbon atoms

Procedimiento

According to the method described in Arch. Pharm. (Weinheim) 328, 271 (1995), addition of two carbon atoms was performed to 15-(2,4,6-triiodophenoxy)pentadecanoic acid by using diethyl malonate to obtain 17-(2,4,6-triiodophenoxy)heptadecanoic acid.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07264790B2uspto-grants-2007_09