Busqueda de Subestructura

12583

CC(C)(C)OC(=O)NC(=N)c1ccc(CNC(=O)[C@@H]2CCc3ncc(NCCc4ccccc4)c(=O)n32)cc1

Reaction #11053

intermediate 2a

Rendimiento 54.0%DOI: 10.6084/m9.figshare.5104873.v1

CCN(CC)c1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)CC2

Reaction #11054

intermediate 3a

Rendimiento 100.0%DOI: 10.6084/m9.figshare.5104873.v1

CC(C)Nc1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)CC2

Reaction #11055

intermediate 4a

Rendimiento 65.0%DOI: 10.6084/m9.figshare.5104873.v1

CCNc1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)CC2

Reaction #11056

intermediate 5a

Rendimiento 60.5%DOI: 10.6084/m9.figshare.5104873.v1

CC(C)(C)OC(=O)NC(=N)c1ccc(CNC(=O)[C@@H]2CCc3ncc(NC4CCCC4)c(=O)n32)cc1

Reaction #11057

intermediate 6a

Rendimiento 57.3%DOI: 10.6084/m9.figshare.5104873.v1

CC(C)CNc1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)CC2

Reaction #11058

intermediate 7a

Rendimiento 79.0%DOI: 10.6084/m9.figshare.5104873.v1

CCCNc1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)CC2

Reaction #11059

intermediate 8a

Rendimiento 46.0%DOI: 10.6084/m9.figshare.5104873.v1

CC(C)CN(CC(C)C)c1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)CC2

Reaction #11060

intermediate 9a

Rendimiento 79.5%DOI: 10.6084/m9.figshare.5104873.v1

CCC(CC)Nc1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)CC2

Reaction #11061

intermediate 11a

Rendimiento 24.0%DOI: 10.6084/m9.figshare.5104873.v1

CC(C)(C)OC(=O)NC(=N)c1ccc(CNC(=O)[C@@H]2CCc3ncc(N(Cc4cccc(C(F)(F)F)c4)C(=O)OCc4ccccc4)c(=O)n32)cc1

Reaction #11083

intermediate 25b

Rendimiento 79.2%DOI: 10.6084/m9.figshare.5104873.v1

C=CCN(C(=O)OCc1ccccc1)c1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OCc3ccccc3)cc1)C[C@@]2(C)NCC

Reaction #11084

Rendimiento 54.0%DOI: 10.6084/m9.figshare.5104873.v1

C=CCN(C(=O)OCc1ccccc1)c1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OCc3ccccc3)cc1)C[C@@]2(C)NC(C)C

Reaction #11085

Rendimiento 28.1%DOI: 10.6084/m9.figshare.5104873.v1

CC(C)(C)OC(=O)NC(=N)c1ccc(CNC(=O)C2CCc3ncc(N(Cc4cccc(C(F)(F)F)c4)C(=O)OCc4ccccc4)c(=O)n32)cc1

Reaction #213420

DOI: 10.1039/C8SC04228D