Reaction #994

Reaction equation

2-Methoxy-cinnamylalcohol

thionylchloride

piperazine

→

salt

N,N'-bis-((E)-3-(2-methoxyphenyl)-2-propenyl)piperazine

Conditions

Workup

1. 1
   Otheras described in Preparation Example 2

Procedure

2-Methoxy-cinnamylalcohol (1.44 g) was chlorinated using thionylchloride. Subsequently, reaction with piperazine and other treatments were performed as described in Preparation Example 2, to thereby obtain 314 mg of a salt as colorless prisms.

Source