Reaction #992720

Reaction equation

2,7-bis(acetylamino)thianthrene

hydrochloric acid

→

2,7-diaminothianthrene

Yield 91.0%

Solvents

ethanol

Conditions

Workup

1. 1
   Temperaturewas heated
2. 2
   Temperatureunder reflux for 6 hours
3. 3
   Filtrationa precipitate was collected by filtration
4. 4
   workup.ADDITIONThe precipitate was added to a mixture of 13.5 ml of concentrated hydrochloric acid and 355 ml of water
5. 5
   Otherthe insoluble matters were separated by filtration
6. 6
   workup.ADDITIONThe filtered mother liquor was poured into an aqueous solution of sodium hydroxide
7. 7
   Filtrationthe precipitate or 2,7-diaminothianthrene was collected by filtration

Procedure

A mixture of 5.75 g (0.0174 mole) of 2,7-bis(acetylamino)thianthrene, 12 ml of concentrated hydrochloric acid, and 140 ml of ethanol was heated under reflux for 6 hours. The reaction mixture was cooled to room temperature and a precipitate was collected by filtration. The precipitate was added to a mixture of 13.5 ml of concentrated hydrochloric acid and 355 ml of water and the insoluble matters were separated by filtration. The filtered mother liquor was poured into an aqueous solution of sodium hydroxide and the precipitate or 2,7-diaminothianthrene was collected by filtration. The yield was 3.7 g (0.0158 mole, 91% yield) and the purity was 88.2 area % (HPLC, 254 nm).

Source