Reaction #985287

Reaction equation

diisobutylaluminium chloride

[8-(dimethylamino)naphth-1-yl]lithium

→

[8-(dimethylamino)naphth-1-yl]diisobutylaluminium

Solvents

diethyl ether

Conditions

Workup

1. 1
   Otherthe reaction
2. 2
   FiltrationFiltration
3. 3
   Otherthrough a D4 frit and removal of the solvent
4. 4
   workup.DISTILLATIONby distillation

Procedure

9.5 g (0.048 mmol) of diisobutylaluminium chloride were added dropwise to a suspension, cooled to −40° C., of 12.1 g (0.048 mmol) of [8-(dimethylamino)naphth-1-yl]lithium etherate and 100 ml of diethyl ether in an inert nitrogen atmosphere. After slow warming to room temperature, the mixture was stirred for a further 24 hours in order to complete the reaction. Filtration through a D4 frit and removal of the solvent by distillation gave 10.6 g of [8-(dimethylamino)naphth-1-yl]diisobutylaluminium (71%) as a colourless, oily liquid by fractional distillation from the residue.

Source