Reaction #985256
ord-24a34c2f2b9348b9894262d50538ecf8
Reaction equation
trans-4-Nitrocinnamyl chloride
2-aminothiophenol
sodium carbonate
→
product 11
Yield 85.1%
Trans-2-(4-Nitrophenylethenyl)benzothiazole
Yield 85.1%
Reagents
None
Conditions
Detailed conditions
See reaction.notes.procedure_details.
Workup
- 1FiltrationThe participate was collected by filtration under reduced pressure
- 2OtherRecrystallization from methanol
Procedure
trans-4-Nitrocinnamyl chloride 10 (1.77 g, 9.5 mmol, 1.2 eq.) in DMF (20 ml) was added dropwise to a solution of 2-aminothiophenol 9 (1.0 g, 8.0 mmol) in DMF(15 ml) at room temperature. The reaction mixture was stirred at room temperature for overnight. The reaction mixture was poured into a solution of 10% sodium carbonate (100 ml). The participate was collected by filtration under reduced pressure. Recrystallization from methanol gave 1.92 g (85.1%) of the product 11.