Reaction #95959

Reaction equation

diethylenetriamine

propyl 3-formylpropionate

octylic acid

→

4-octamidoethyl-2,3,6,7-tetrahydro-1,4-diazocin-5-one

Conditions

Workup

1. 1
   workup.DISTILLATIONAt 140° to 145° C., 18 g of water and 60 g of propyl alcohol were distilled off
2. 2
   Otherto proceed at 150° to 155° C.
3. 3
   Otherto distil off 18 g of water

Procedure

Into an apparatus similar to that in Example 1, were charged 103.1 g (1 mole) of diethylenetriamine and 144.2 g (1 mole) of propyl 3-formylpropionate. At 140° to 145° C., 18 g of water and 60 g of propyl alcohol were distilled off. Then, after adding 144.2 g (1 mole) of octylic acid, the reaction was allowed to proceed at 150° to 155° C. to distil off 18 g of water, obtaining 4-octamidoethyl-2,3,6,7-tetrahydro-1,4-diazocin-5-one.

Source