Reaction #95323

Reaction equation

product

2-isopropyl-2-p-chlorophenyl-acetic acid

thionyl chloride

→

2-isopropyl-2-p-chlorophenyl acetyl chloride

Solvents

Conditions

Workup

1. 1
   Temperaturethe mixture was refluxed for 4 hours
2. 2
   Temperaturewas then cooled
3. 3
   OtherThe mixture was evaporated to dryness

Procedure

10 g of the product of Step D were added to a mixture of 50 ml of petroleum ether (b.p.=35°-70° C.) and 20 ml of thionyl chloride and the mixture was refluxed for 4 hours and was then cooled. The mixture was evaporated to dryness to obtain 10.8 g of D 2-isopropyl-2-p-chlorophenyl acetyl chloride.

Source