Reaction #94401

Reaction equation

2-[o-(β-chloro-ethoxy)-styryl]-1-methyl-benzimidazole

dimethylamine

dihydrochloride

→

2-[o-(β-Dimethylamino-ethoxy)-styryl]-1-methyl-benzimidazole

Conditions

Workup

1. 1
   Otheryielding 18% of theory of the compound of the formula ##STR12## which

Procedure

2-[o-(β-Dimethylamino-ethoxy)-styryl]-1-methyl-benzimidazole was prepared from 2-[o-(β-chloro-ethoxy)-styryl]-1-methyl-benzimidazole and dimethylamine, and the free base was converted into its dihydrochloride, yielding 18% of theory of the compound of the formula ##STR12## which had a melting point of 208° C.

Source