Reaction #944001

ord-5be77a34cfbb4d90af8a382763010306

Reaction equation

C=CC=O
acrolein
COc1ccc(C(C#N)Nc2ccc(SC)cc2)cc1
α-(4-methoxyphenyl)-α-(4-methylthioanilino)acetonitrile
COc1ccc(C=Nc2ccc(SC)cc2)cc1
title compound
COc1ccc(C=Nc2ccc(SC)cc2)cc1
N-(4-Methoxybenzylidene)-4-methylthioaniline

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

Following a procedure similar to that described in Example 21 (iii), but using α-(4-methoxyphenyl)-α-(4-methylthioanilino)acetonitrile [prepared as described in step (ii) above] and acrolein as starting materials, the title compound was obtained as a white powder (yield 9%), melting at 183-184° C.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: USRE039420E1uspto-grants-2006_12