Reaction #937078

Reaction equation

5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthol

4-bromobenzaldehyde

→

4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyloxy)benzaldehyde

Conditions

Workup

1. 1
   Otherwere obtained
2. 2
   Otherafter purification by chromatography on a silica column
3. 3
   Washeluted with a mixture of dichloromethane and hexane (50/50)

Procedure

In a manner similar to Example 1(a) above, by the reaction of 5.3 g (15 mmol) of 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthol with 3.1 g (16.5 mmol) of 4-bromobenzaldehyde, 2.4 g of the expected aldehyde of melting point 75-6° C. were obtained after purification by chromatography on a silica column eluted with a mixture of dichloromethane and hexane (50/50).

Source