Reaction #93612

Reaction equation

5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid

dicyclohexylamine

→

product

Yield 59.9%

Dicyclohexylammonium 5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoate

Yield 59.9%

Solvents

glyme

Conditions

Workup

1. 1
   OtherThe solvent is removed in vacuo
2. 2
   Otherthe residue triturated with petroleum ether (bp 30°-60° C.)
3. 3
   Otherdried

Procedure

5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid (3.0 g, 0.0083 mole) is dissolved in glyme (20 ml) and dicyclohexylamine (1.64 g, 0.0091 mole) is added at room temperature while stirring. The solvent is removed in vacuo, the residue triturated with petroleum ether (bp 30°-60° C.), and dried to give 2.7 g of product, mp 197°-9° C. Anal. Calcd. for C26H30ClF3N2O5 : C, 57.51; H, 5.56; N, 5.15; Cl, 6.53; F, 10.49. Found C, 57.25; H, 5.71; N, 5.55, Cl, 6.40; F, 10.24.

Source