Reaction #927228

ord-390a5630d1a84acc809fd0c60ccb3b0e

Reaction equation

CC1=Nc2ccccc2C1(C)C
2,3,3-trimethylindolenine
O=C(O)CCCCCBr
6-bromohexanoic acid
→
CC1[NH+](CCCCCC(=O)O)c2ccccc2C1(C)C.[Br-]
N-(5-carboxypentyl)-2,3,3-trimethylindolinium bromide

Reactants

CC1=Nc2ccccc2C1(C)C
2,3,3-trimethylindolenine
O=C(O)CCCCCBr
6-bromohexanoic acid

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

N-(5-carboxypentyl)-2,3,3-trimethylindolinium bromide was prepared by the process set forth in Example IA with 2,3,3-trimethylindolenine and 6-bromohexanoic acid to produce 2.43 grams (71.2 percent yield) of yellow crystals. 1H and 13C NMR spectra indicated the following:

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06365312B1uspto-grants-2002_04