Reaction #91963

Reaction equation

3-methyl-4-[(2-methylpropan-2-yl)oxycarbonyl]morpholine-3-carboxylic acid

trifluoroacetic acid

→

3-methylmorpholine-3-carboxylic acid

Solvents

DCM

Conditions

Workup

1. 1
   Concentrationconcentrated under the vacuum
2. 2
   OtherThe residue was used directly in next step without further purification

Procedure

To a solution of 3-methyl-4-[(2-methylpropan-2-yl)oxycarbonyl]morpholine-3-carboxylic acid (Accela ChemBio Co., Ltd., CAS: 1052680-53-1, 50 mg, 0.2.0 mmol) in DCM (1 ml) was added trifluoroacetic acid (1 mL) dropwise at room temperature. The resulting mixture was stirred at room temperature for one hour and then concentrated under the vacuum. The residue was used directly in next step without further purification,

Source