Reaction #9106

ord-597359ad5d8d4774b20427c336c03943

Reaction equation

c1ccc(-c2cc3ccccc3[nH]2)cc1
2-phenyl-1H-indole
Cc1ccccc1C=[N+]1CCCCC1.[Cl-]
1-(2-methyl-benzylidene)-piperidinium chloride
→
Cc1ccccc1C(c1c(-c2ccccc2)[nH]c2ccccc12)N1CCCCC1
2-Phenyl-3-(piperidin-1-yl-o-tolylmethyl)-1H-indole

Reactants

c1ccc(-c2cc3ccccc3[nH]2)cc1
2-phenyl-1H-indole
Cc1ccccc1C=[N+]1CCCCC1.[Cl-]
1-(2-methyl-benzylidene)-piperidinium chloride

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The preparation was carried out in accordance with general synthesis instructions 4 from 2-phenyl-1H-indole and 1-(2-methyl-benzylidene)-piperidinium chloride.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07091220B2uspto-grants-2006_08