Reaction #89981

ord-d810174b918b44b8ac9f30d1743b782f

Reaction equation

CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
Compound A6
CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
8-Hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
OCCBr
2-bromo-ethanol
→
CC1(C)c2cc(OCCO)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
title compound
CC1(C)c2cc(OCCO)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
8-(2-Hydroxyethoxy)-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

Reactants

CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
Compound A6
CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
8-Hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
OCCBr
2-bromo-ethanol

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherUnder the same conditions as the method for synthesizing Compound A7-17

Procedure

Under the same conditions as the method for synthesizing Compound A7-17, the title compound was prepared from Compound A6 and 2-bromo-ethanol.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09440922B2uspto-grants-2016_09