Reaction #8963

ord-968e7d53e00a490e98435e4b46f07c1f

Reaction equation

Cc1cc(C#Cc2c[nH]c(C)n2)ccn1
2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine
N#CCBr
bromoacetonitrile
Cc1cc(C#Cc2cn(CC#N)c(C)n2)ccn1
title compound
Cc1cc(C#Cc2cn(CC#N)c(C)n2)ccn1
[2-Methyl-4-(2-methyl-pyridin-4-ylethynyl)-imidazol-1-yl]-acetonitrile

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The title compound, MS: m/e=237.2 (M+H+), was prepared in accordance with the general method of example 1 from 2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and bromoacetonitrile.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07091222B2uspto-grants-2006_08