Reaction #8962

ord-bad62e359d54446995609ea47249323a

Reaction equation

Cc1cc(C#Cc2c[nH]c(C)n2)ccn1
2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine
BrCC1CCC1
bromomethyl-cyclobutane
Cc1cc(C#Cc2cn(CC3CCC3)c(C)n2)ccn1
title compound
Cc1cc(C#Cc2cn(CC3CCC3)c(C)n2)ccn1
4-(1-Cyclobutylmethyl-2-methyl-1H-imidazol-4-ylethynyl)-2-methyl-pyridine

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The title compound, MS: m/e=266.2 (M+H+), was prepared in accordance with the general method of example 1 from 2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and bromomethyl-cyclobutane.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07091222B2uspto-grants-2006_08