Reaction #85014

Reaction equation

4-chloro-2-(2,5-dimethoxypyridin-4-yl)benzonitrile

pyridinium hydrochloride

→

4-Chloro-2-(5-methoxy-2-oxo-1,2-dihydropyridin-4-yl)benzonitrile

Conditions

Procedure

7.23 g (purity 92%, 24.21 mmol) of 4-chloro-2-(2,5-dimethoxypyridin-4-yl)benzonitrile and pyridinium hydrochloride were reacted according to General Method 3A. Yield: 6.66 g (purity 91%, 96% of theory)

Source