Reaction #84025

ord-d872591027264a99a4c357f08f23f73a

Reaction equation

O=C(Cl)C(=O)Cl
Oxalyl chloride
CC(C)(C)O
t-butyl alcohol
→
CC(C)(C)OC(=O)C(=O)Cl
Compound 34
CC(C)(C)OC(=O)C(=O)Cl
Chloro-Oxo-Acetic Acid t-Butyl Ester

Reactants

O=C(Cl)C(=O)Cl
Oxalyl chloride
CC(C)(C)O
t-butyl alcohol

Reagents

None

Solvents

CCOCC
ether

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherThe solvent was evaporated under vacuum

Procedure

Oxalyl chloride (232 μL, 2.8 mmol) and t-butyl alcohol (228 μL) were combined in ether (6.7 mL) under nitrogen at 0° C. The resulting mixture was stirred for 30 minutes at room temperature. The solvent was evaporated under vacuum to form Compound 34.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09433598B2uspto-grants-2016_09