Reaction #80940

Reaction equation

Thionyl chloride

3,6,9-trioxadecanoic acid

→

3,6,9-trioxadecanoyl chloride

Conditions

Workup

1. 1
   workup.ADDITIONUpon completion of addition
2. 2
   Temperaturethe reaction mixture was warmed
3. 3
   Temperatureto reflux where it
4. 4
   TemperatureThe reaction mixture was cooled

Procedure

Thionyl chloride, 8.0 grams (0.112 mole) was stirred, and 10.0 grams (0.056 mole) of 3,6,9-trioxadecanoic acid was added dropwise during a 45 minute period. Upon completion of addition, the reaction mixture was warmed to reflux where it stirred for 45 minutes. The reaction mixture was cooled, yielding 3,6,9-trioxadecanoyl chloride. An 80% yield of acid chloride was assumed.

Source