Reaction #806261

ord-07659df43e924ec8bbdf5a523c1f2fa1

Reaction equation

CC(C)C(O)C(C)(C)CO
2,2,4-trimethylpentan-1,3-diol
CC(C)CBr
isobutyl bromide
→
CC(C)COCC(C)(C)C(O)C(C)C
1-(2-methylpropyloxy)-2,2,4-trimethylpentan-3-ol
Yield 88.0%

Reactants

CC(C)C(O)C(C)(C)CO
2,2,4-trimethylpentan-1,3-diol
CC(C)CBr
isobutyl bromide

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

Treatment of 2,2,4-trimethylpentan-1,3-diol with isobutyl bromide employing the alkylation reaction conditions described above provided 1-(2-methylpropyloxy)-2,2,4-trimethylpentan-3-ol in 88.0% yield (355.5 g, b.p.=81–82 C./2.5 mmHg).

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07132391B2uspto-grants-2006_11