Reaction #806260

ord-9965e028ecd8420d9bb32cebd1a8c419

Reaction equation

CC(C)C(O)C(C)(C)CO
2,2,4-trimethylpentan-1,3-diol
CCBr
ethyl bromide
→
CCOCC(C)(C)C(O)C(C)C
1-ethoxy-2,2,4-trimethylpentan-3-ol
Yield 90.0%

Reactants

CC(C)C(O)C(C)(C)CO
2,2,4-trimethylpentan-1,3-diol
CCBr
ethyl bromide

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

Treatment of 2,2,4-trimethylpentan-1,3-diol with ethyl bromide employing the alkylation reaction conditions described above provided 1-ethoxy-2,2,4-trimethylpentan-3-ol in 90.0% yield (313.2 g, b.p.=79–80 C./3.2 mmHg).

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07132391B2uspto-grants-2006_11