Reaction #806242

ord-1a1f029044774aacaec1cb3388ce98d1

Reaction equation

COc1ccccc1O
guaiacol
O=S(=O)(O)O
sulfuric acid
O=S(=O)(O)O
sulfuric acid
O=S(=O)(O)O
sulfuric acid
COc1ccccc1O
guaiacol
COc1ccccc1O
guaiacol
COc1ccccc1O
guaiacol
→
COc1cc(S(=O)(=O)O)ccc1O
guaiacolsulfonic acid

Reactants

COc1ccccc1O
guaiacol
O=S(=O)(O)O
sulfuric acid
O=S(=O)(O)O
sulfuric acid
O=S(=O)(O)O
sulfuric acid
COc1ccccc1O
guaiacol
COc1ccccc1O
guaiacol
COc1ccccc1O
guaiacol

Reagents

None

Solvents

O
water
O
Water

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherThe weight of available stock guaiacol, purified reagent, that
  2. 2
    Otherpurified reagent from the available stock bottle
  3. 3
    workup.ADDITIONwas added to the bottle

Procedure

A solution of guaiacolsulfonic acid in sulfuric acid was prepared. Water in the recirculating water bath was heated to 65 degrees Centigrade. The weight of available stock guaiacol, purified reagent, that contained 1.63 moles of guaiacol was calculated. The amount of available stock of sulfuric acid NF that contained 3.41 moles of sulfuric acid was calculated. A 1 liter Corning Pyrix bottle No. 1395 was placed on the Mettler PG-5002-S balance. A 600 mL beaker was filled with approximately 400 mL guaiacol, purified reagent from the available stock bottle. A quantity of 1.63 moles of guaiacol as guaiacol, purified reagent by weight from the beaker was added to the bottle.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07132111B2uspto-grants-2006_11