Reaction #80384

Reaction equation

N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-6-bromohexanamide

2-mercaptoethanol

→

title compound

Yield 94.0%

N-[4-(4-Piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-6-(2-hydroxyethylthio)hexanamide

Yield 94.0%

Conditions

Procedure

Following a procedure similar to that described in Example 67(b), but using N-[4-(4-piperidinomethyl-2-pyridyloxy)-cis-2-butenyl]-6-bromohexanamide [prepared as described in step (a) above] and 2-mercaptoethanol as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a 94% yield.

Source