Reaction #78722

ord-ec724e03576642ca9d8d97ceaaf5a08b

Reaction equation

Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(Nc3nc(C)cc(C)c3N)cc2)cc1
N-{[(2-{4-[(3-amino-4,6-dimethyl-2-pyridinyl)amino]phenyl}ethyl)amino]carbonyl}-4-methylbenzenesulfonamide
O=C(O)CCC(=O)c1ccccc1
3-benzoylpropionic acid
→
Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(-n3c(CCC(=O)c4ccccc4)nc4c(C)cc(C)nc43)cc2)cc1
title compound
Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(-n3c(CCC(=O)c4ccccc4)nc4c(C)cc(C)nc43)cc2)cc1
N-{[(2-{4-[5,7-DIMETHYL-2-(3-OXO-3-PHENYLPROPYL)-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL]PHENYL}ETHYL)AMINO]CARBONYL}-4-METHYLBENZENESULFONAMIDE

Reactants

Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(Nc3nc(C)cc(C)c3N)cc2)cc1
N-{[(2-{4-[(3-amino-4,6-dimethyl-2-pyridinyl)amino]phenyl}ethyl)amino]carbonyl}-4-methylbenzenesulfonamide
O=C(O)CCC(=O)c1ccccc1
3-benzoylpropionic acid

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The title compound was prepared according to the procedure described in Example 241 from N-{[(2-{4-[(3-amino-4,6-dimethyl-2-pyridinyl)amino]phenyl}ethyl)amino]carbonyl}-4-methylbenzenesulfonamide (step 4 of Example 162) and 3-benzoylpropionic acid.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06710054B2uspto-grants-2004_03