Reaction #76730

Reaction equation

arginine-mono-methacrylamide hydrochloride

→

Arginine-methacrylamide

Solvents

water

Conditions

Workup

1. 1
   Otherbubbled with nitrogen gas for 1 hour
2. 2
   workup.ADDITIONPotassium persulfate(60 mg) was added to the solution
3. 3
   workup.DISSOLUTIONdissolved in it
4. 4
   TemperatureThe reaction mixture was refluxed
5. 5
   Temperatureby heating for 3 hours
6. 6
   workup.ADDITIONpoured into acetone
7. 7
   Otherso that precipitates
8. 8
   workup.ADDITIONacetone was again added to the
9. 9
   Otherprecipitates
10. 10
    Otherobtained mixture
11. 11
    FiltrationThe deposition was collected by filtration
12. 12
    Otherdried
13. 13
    Otherto obtain the target polymer (white powder, 3.05 g)

Procedure

The obtained arginine-mono-methacrylamide hydrochloride(4.84 g) was dissolved in 40 ml of distilled water, and bubbled with nitrogen gas for 1 hour. Potassium persulfate(60 mg) was added to the solution, and dissolved in it. The reaction mixture was refluxed by heating for 3 hours, then cooled to room temperature, and poured into acetone, so that precipitates were deposited. The supernatant was discarded, and acetone was again added to the precipitates and obtained mixture was stirred. The deposition was collected by filtration and dried to obtain the target polymer (white powder, 3.05 g).

Source