Reaction #74876

Reaction equation

2,4-dinitrofluorobenzene

1-(2-acetamidoethyl)tetrazole-5-thiol

triethylamine

→

1-(2-acetamidoethyl)-5-(2,4-dinitrophenylthio)tetrazole

Solvents

acetone

acetone

Conditions

Workup

1. 1
   FiltrationThe solid material was collected by filtration
2. 2
   Otherrecrystallized from acetonitrile

Procedure

A solution of 9.3 g. (0.050 mol) of 2,4-dinitrofluorobenzene in 50 ml. of acetone was added to a solution of 9.35 g. (0.050 mol) of 1-(2-acetamidoethyl)tetrazole-5-thiol and 6.85 ml. (0.050 mol) of triethylamine in 100 ml. of acetone and the reaction mixture was stirred for 1 hour. The solid material was collected by filtration and recrystallized from acetonitrile to give 1-(2-acetamidoethyl)-5-(2,4-dinitrophenylthio)tetrazole, mp 197°-198° C.

Source