Reaction #74727

ord-8b4f028c06f64f1aa0a2c8a9644c1d5b

Reaction equation

Cc1cccc(Cl)c1Nc1ccccc1CC(=O)NO
[o-(3-chloro-o-toluidino)-phenyl]-acetohydroxamic acid
Cc1cccc(Cl)c1Nc1ccccc1CC(=O)Oc1ccc([N+](=O)[O-])cc1
[o-(3-chloro-o-toluidino)-phenyl]-acetic acid-p-nitrophenyl ester
→
O=C(Cc1ccccc1Nc1c(Cl)cccc1Cl)NO
[o-(2,6-dichloroanilino)-phenyl]-acetohydroxamic acid

Reactants

Cc1cccc(Cl)c1Nc1ccccc1CC(=O)NO
[o-(3-chloro-o-toluidino)-phenyl]-acetohydroxamic acid
—
ether petroleum ether
Cc1cccc(Cl)c1Nc1ccccc1CC(=O)Oc1ccc([N+](=O)[O-])cc1
[o-(3-chloro-o-toluidino)-phenyl]-acetic acid-p-nitrophenyl ester

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

[o-(3-chloro-o-toluidino)-phenyl]-acetohydroxamic acid, M.P. 135°-136° (from ether/petroleum ether), starting with [o-(3-chloro-o-toluidino)-phenyl]-acetic acid-p-nitrophenyl ester.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04173577uspto-grants-1979_11