Reaction #74337

ord-4cffadb3436c489e8f1082a611e590eb

Reaction equation

N[C@@H](Cc1c[nH]cn1)C(=O)O

(2S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid

NC(=S)NC1CCCCCC1

N-cycloheptylthiourea

→

O=C1N=C(NC2CCCCCC2)SC1Cc1c[nH]cn1

2-(cycloheptylamino)-5-(1H-imidazol-4-ylmethyl)-1,3-thiazol-4(5H)-one

Reactants

(2S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid

N-cycloheptylthiourea

Reagents

None

Conditions

Detailed conditions

See reaction.notes.procedure_details.

Workup

1
OtherSynthesis

Procedure

Synthesis was performed from (2S)-2-amino-3-(1H-imidazol-4-yl)propanoic acid and N-cycloheptylthiourea according to Method E and C.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08541592B2uspto-grants-2013_09